GLOUCESTER's Jonny May and Billy Twelvetrees have been named in the England side to play Ireland at Twickenham on Saturday (4pm).
May will start on the wing in what will be his Test debut at rugby HQ while Twelvetrees retains his spot at inside centre.
Number eight Ben Morgan will be on the bench with Billy Vunipola starting.
England have made one change to the starting XV which triumphed 20-0 over Scotland at Murrayfield, with David Wilson replacing the injured Dan Cole at tighthead prop.
Bath fly-half George Ford has been named on the bench for centre Brad Barritt.
Meanwhile Billy Burns and Ross Moriarty have retained their starting spots in the England Under-20s outfit that take on their Irish counterparts at Franklin's Gardens.
Nick Walshe has made five changes to the team with IRB Junior World Championship winners Harry Sloan and Scott Wilson handed their first starts of the campaign and Alex Lundberg, Harry Thacker and Joel Conlon all coming in.